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Before Using
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of rotavirus vaccine live pentavalent in infants younger than 6 weeks of age or older than 32 weeks of age. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of rotavirus vaccine live pentavalent in geriatric patients.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Receiving this vaccine with any of the following medicines is not recommended. Your doctor may decide not to use this vaccine or change some of the other medicines you take.
- Aclarubicin
- Aldesleukin
- Altretamine
- Amonafide
- Amsacrine
- Asparaginase
- Azacitidine
- Betamethasone
- Bleomycin
- Broxuridine
- Busulfan
- Capecitabine
- Carboplatin
- Carmustine
- Chlorambucil
- Cisplatin
- Cladribine
- Corticotropin
- Cortisone
- Cosyntropin
- Cyclophosphamide
- Cytarabine
- Cytarabine Liposome
- Dacarbazine
- Dactinomycin
- Daunorubicin
- Daunorubicin Citrate Liposome
- Decitabine
- Deflazacort
- Dexamethasone
- Docetaxel
- Doxifluridine
- Doxorubicin Hydrochloride
- Doxorubicin Hydrochloride Liposome
- Edatrexate
- Eflornithine
- Epirubicin
- Estramustine
- Etoposide
- Floxuridine
- Fludarabine
- Fludrocortisone
- Fluocortolone
- Fluorouracil
- Fotemustine
- Gallium Nitrate
- Gemcitabine
- Hydrocortisone
- Hydroxyurea
- Idarubicin
- Ifosfamide
- Interferon Alfa
- Interferon Alfacon-1
- Interferon Beta
- Interferon Beta-1a
- Interferon Beta-1b
- Interferon Gamma
- Irinotecan
- Lomustine
- Mechlorethamine
- Melphalan
- Mercaptopurine
- Methotrexate
- Methylprednisolone
- Mitolactol
- Mitomycin
- Mitotane
- Mitoxantrone
- Oxaliplatin
- Paclitaxel
- Paclitaxel Protein-Bound
- Paramethasone
- Pegaspargase
- Pentostatin
- Pipobroman
- Pirarubicin
- Plicamycin
- Prednisolone
- Prednisone
- Procarbazine
- Raltitrexed
- Rituximab
- Streptozocin
- Teceleukin
- Tegafur
- Teniposide
- Thioguanine
- Thiotepa
- Topotecan
- Treosulfan
- Triamcinolone
- Trimetrexate
- Trofosfamide
- Uracil Mustard
- Vinblastine
- Vincristine
- Vincristine Sulfate Liposome
- Vindesine
- Vinorelbine
Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aclarubicin
- Adalimumab
- Aldesleukin
- Alemtuzumab
- Altretamine
- Amonafide
- Amsacrine
- Asparaginase
- Azacitidine
- Azathioprine
- Bleomycin
- Broxuridine
- Busulfan
- Capecitabine
- Carboplatin
- Carmustine
- Certolizumab Pegol
- Chlorambucil
- Cisplatin
- Cladribine
- Cyclophosphamide
- Cytarabine
- Cytarabine Liposome
- Dacarbazine
- Dactinomycin
- Daunorubicin
- Daunorubicin Citrate Liposome
- Decitabine
- Docetaxel
- Doxifluridine
- Doxorubicin Hydrochloride
- Doxorubicin Hydrochloride Liposome
- Edatrexate
- Eflornithine
- Epirubicin
- Estramustine
- Etanercept
- Etoposide
- Everolimus
- Fingolimod
- Floxuridine
- Fludarabine
- Fluorouracil
- Fotemustine
- Gallium Nitrate
- Gemcitabine
- Golimumab
- Hydroxyurea
- Idarubicin
- Ifosfamide
- Irinotecan
- Lomustine
- Mechlorethamine
- Melphalan
- Mercaptopurine
- Methotrexate
- Mitolactol
- Mitomycin
- Mitotane
- Mitoxantrone
- Mycophenolic Acid
- Oxaliplatin
- Paclitaxel
- Pegaspargase
- Pentostatin
- Pipobroman
- Pirarubicin
- Plicamycin
- Procarbazine
- Raltitrexed
- Rilonacept
- Rituximab
- Sirolimus
- Streptozocin
- Tacrolimus
- Teceleukin
- Tegafur
- Temsirolimus
- Teniposide
- Thioguanine
- Thiotepa
- Topotecan
- Treosulfan
- Trimetrexate
- Trofosfamide
- Uracil Mustard
- Ustekinumab
- Vinblastine
- Vincristine
- Vincristine Sulfate Liposome
- Vindesine
- Vinorelbine
Receiving this vaccine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abatacept
- Leflunomide
- Vaccinia Immune Globulin, Human
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
- Blood disorders (e.g., leukemia, lymphoma) or
- Receiving immunosuppressive treatment (e.g., corticosteroids) or
- Weakened immune system (e.g., HIV or AIDS)—There is no evidence that this vaccine is safe or effective in infants with these conditions.
- Chronic diarrhea or
- Digestive problems (e.g., abdominal or stomach surgery, active stomach illness) or
- Failure to thrive (poor weight gain and physical growth failure)—Use with caution. There is no evidence that this vaccine is safe or effective in infants with these conditions.
- Illness with fever, moderate or severe—Your child may need to wait until he or she feels better before receiving the vaccine.
- Severe combined immunodeficiency disease or SCID (an inherited disease), history of—Should not be used in patients with this condition.
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