Nortriptyline (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Agitation
• Anxiety
• Black, tarry stools
• Bleeding and bruising
• Bleeding gums
• Blood in the urine or stools
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest pain or discomfort
• Clay-colored stools
• Cold sweats
• Confusion about identity, place, and time false beliefs that cannot be changed by facts
• Continuing ringing or buzzing or other unexplained noise in the ears
• Convulsions
• Cool, pale skin
• Cough or hoarseness
• Dark urine
• Decrease in the frequency of urination
• Decreased urine output or volume
• Depression
• Difficulty in passing urine (dribbling)
• Difficulty in speaking
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Double vision
• Drooling
• Dry mouth
• Fast, pounding, or irregular heartbeat or pulse
• Feeling of warmth
• Feeling, seeing, or hearing things that are not there
• Feeling that others are watching you or controlling your behavior
• Feeling that others can hear your thoughts
• Fever with or without chills
• Flushed, dry skin
• Fruit-like breath odor
• General feeling of tiredness or weakness
• Headache
• Hearing loss
• Hostility
• Hyperventilation
• Inability to move the arms, legs, or facial muscles
• Inability to speak
• Increased hunger
• Increased need to urinate
• Increased thirst
• Increased urination
• Irritability
• Itching
• Lack of coordination
• Lethargy
• Loss of appetite
• Loss of balance control
• Lower back or side pain
• Mood or mental changes
• Muscle spasm or jerking of all extremities
• Muscle trembling, jerking, or stiffness
• Muscle twitching
• Nausea
• Nightmares
• Pain or discomfort in the arms, jaw, back, or neck
• Painful or difficult urination
• Panic
• Passing urine more often
• Perspiration
• Pinpoint red or purple spots on the skin
• Pounding in the ears
• Rapid weight gain
• Rash
• Redness of the face, neck, arms, and occasionally, upper chest
• Restlessness
• Seizures
• Shakiness and unsteady walk
• Shortness of breath
• Shuffling walk
• Sleeplessness
• Slow speech
• Slurred speech
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Stiffness of the limbs
• Stupor
• Sudden loss of consciousness
• Sweating
• Swelling of the face, ankles, legs, or hands
• Swollen glands
• Talking, feeling, and acting with excitement
• Trouble in holding or releasing urine
• Trouble sleeping
• Twisting movements of the body uncontrolled movements, especially of the face, neck, and back
• Unable to sleep
• Unpleasant breath odor
• Unsteadiness, awkwardness, trembling, or other problems with muscle control or coordination
• Unusual behavior
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Vomiting of blood
• Weakness in the arms, hands, legs, or feet
• Weight gain or loss
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach cramps
• Bigger, dilated, or enlarged pupils (black part of the eye)
• Black tongue
• Bloating
• Decreased interest in sexual ability or desire
• Diarrhea
• Difficulty having a bowel movement (stool)
• Enlargement of the breast
• Hair loss or thinning of the hair
• Heartburn
• Hives or welts
• Inability to have or keep an erection
• Increase in sexual ability or desire
• Increased sensitivity of the eyes to light
• Increased sensitivity of the skin to sunlight
• Increased urge to urinate during the night
• Loss in sexual ability or desire
• Pain or discomfort in the chest, upper stomach, or throat
• Peculiar taste
• Redness or other discoloration of the skin
• Severe sunburn
• Small red or purple spots on the skin
• Swelling of the testicles
• Swelling of the breasts or breast soreness in both females and males
• Swelling or inflammation of the mouth
• Swollen, painful, or tender lymph glands on side of face or neck
• Vision changes
• Waking to urinate at night

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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