Chlorpropamide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Agitation
• Black, tarry stools
• Chills
• Clay-colored stools
• Coma
• Confusion
• Continuing diarrhea
• Continuing stomach pain
• Convulsions
• Dark urine
• Decreased urine output
• Depression
• Diarrhea
• Dizziness
• Fast or irregular heartbeat
• Fever
• Headache
• Hostility
• Increased thirst
• Irritability
• Itching
• Lethargy
• Loss of appetite
• Muscle pain or cramps
• Muscle twitching
• Nausea or vomiting
• Rapid weight gain
• Rash
• Seizures
• Shortness of breath
• Stupor
• Swelling of the face, ankles, or hands
• Unpleasant breath odor
• Unusual tiredness or weakness
• Vomiting of blood
• Yellow eyes or skin

• Anxiety
• Back, leg, or stomach pains
• Bleeding gums
• Blood in the urine or stools
• Blurred vision
• Chest pain
• Cold sweats
• Cool, pale skin
• Cough or hoarseness
• Depression
• Difficulty with breathing
• Fever with or without chills
• Fluid-filled skin blisters
• General body swelling
• General feeling of tiredness or weakness
• Headache
• High fever
• Increased hunger
• Lower back or side pain
• Nervousness
• Nightmares
• Nosebleeds
• Painful or difficult urination
• Pinpoint red spots on the skin
• Sensitivity to the sun
• Shakiness
• Skin thinness
• Slurred speech
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Swollen or painful glands
• Tightness in the chest
• Unusual bleeding or bruising
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Indigestion
• Passing of gas

• Hives or welts
• Redness of the skin
• Weight loss

• Blistering, peeling, or loosening of the skin
• Cracks in the skin
• Loss of heat from the body
• Red, irritated eyes
• Red, swollen skin
• Scaly skin

• Increased sensitivity of the skin to sunlight
• Redness or other discoloration of the skin
• Severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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