Levothyroxine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Chest pain or discomfort
• Decreased urine output
• Difficult or labored breathing
• Difficulty with swallowing
• Dilated neck veins
• Extreme fatigue
• Fainting
• Fast, slow, irregular, pounding, or racing heartbeat or pulse
• Fever
• Heat intolerance
• Hives or welts
• Increased blood pressure
• Increased pulse
• Irregular breathing
• Irritability
• Menstrual changes
• Nausea
• Pain or discomfort in the arms, jaw, back, or neck
• Shortness of breath
• Skin itching, rash, or redness
• Sweating
• Swelling of the eyes, face, lips, throat, or tongue
• Tightness in the chest
• Tremors
• Troubled breathing

• Blurred or double vision
• Dizziness
• Eye pain
• Lack or slowing of normal growth in children
• Limp or walk favoring one leg
• Pain in the hip or knee
• Seizures
• Severe headache

Get emergency help immediately if any of the following symptoms of overdose occur:

• Change in consciousness
• Cold, clammy skin
• Confusion
• Disorientation
• Fast or weak pulse
• Lightheadedness
• Loss of consciousness
• Sudden headache
• Sudden loss of coordination
• Sudden slurring of speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach cramps
• Change in appetite
• Crying
• Diarrhea
• False or unusual sense of well-being
• Fear
• Feeling not well or unhappy
• Feeling of discomfort
• Feeling of warmth
• Feeling things are not real
• Feelings of suspicion and distrust
• Hair loss
• Headache
• Increased appetite
• Mental depression
• Muscle weakness
• Nervousness
• Quick to react or overreact emotionally
• Rapidly changing moods
• Redness of the face, neck, arms, and occasionally, upper chest
• Restlessness
• Trouble getting pregnant
• Trouble sitting still
• Unusual tiredness or weakness
• Vomiting
• Weight gain
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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