Tolazamide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Chills
• Clay-colored stools
• Dark urine
• Diarrhea
• Difficulty swallowing
• Dizziness
• Fast heartbeat
• Fever
• Headache
• Hives
• Itching
• Loss of appetite
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rash
• Shortness of breath
• Skin rash
• Tightness in chest
• Unpleasant breath odor
• Unusual tiredness or weakness
• Vomiting of blood
• Wheezing
• Yellow eyes or skin

• Agitation
• Back, leg, or stomach pains
• Black, tarry stools
• Bleeding gums
• Blood in urine or stools
• Chest pain
• Coma
• Confusion
• Convulsions
• Cough or hoarseness
• Decreased urine output
• Depression
• Difficulty breathing
• Fast or irregular heartbeat
• Fatigue
• Fever with or without chills
• Fluid-filled skin blisters
• General body swelling
• General feeling of tiredness or weakness
• Hostility
• Increased thirst
• Irritability
• Itching of the skin
• Lethargy
• Light-colored stools
• Lower back or side pain
• Muscle pain or cramps
• Muscle twitching
• Nausea or vomiting
• Nosebleeds
• Painful or difficult urination
• Pale skin
• Pinpoint red spots on skin
• Rapid weight gain
• Seizures
• Sensitivity to the sun
• Skin thinness
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Stupor
• Swelling of the face, ankles, or hands
• Swollen or painful glands
• Unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

• Anxiety
• Cold sweats
• Cool, pale skin
• Increased hunger
• Nervousness
• Nightmares
• Shakiness
• Slurred speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Indigestion
• Passing of gas

• Feeling of constant movement of self or surroundings
• Sensation of spinning

• Redness or other discoloration of skin
• Severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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