Glimepiride (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Difficulty with swallowing
  • Dizziness
  • Fast heartbeat
  • Hives
  • Itching
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Shortness of breath
  • Skin rash
  • Tightness in the chest
  • Unusual tiredness or weakness
  • Wheezing
Incidence not known
  • Abdominal or stomach pain
  • Agitation
  • Back, leg, or stomach pains
  • Bleeding gums
  • Blistering, peeling, or loosening of the skin
  • Bloating of abdomen
  • Blood in the urine or stools
  • Bloody, black, or tarry stools
  • Chest pain
  • Chills
  • Coma
  • Confusion
  • Cough or hoarseness
  • Dark urine
  • Decreased urine output
  • Depression
  • Diarrhea
  • Difficulty with breathing
  • Fever with or without chills
  • Fluid-filled skin blisters
  • General body swelling
  • General tiredness and weakness
  • Headache
  • High fever
  • Hostility
  • Irritability
  • Joint or muscle pain
  • Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • Lethargy
  • Light-colored stools
  • Loss of appetite
  • Lower back or side pain
  • Muscle twitching
  • Nausea and vomiting
  • Nosebleeds
  • Painful or difficult urination
  • Pale skin
  • Pinpoint red spots on the skin
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Rapid weight gain
  • Red, irritated eyes
  • Red skin lesions, often with a purple center
  • Seizures
  • Sensitivity to the sun
  • Skin thinness
  • Sore throat
  • Sores, ulcers, or white spots on the lips or in the mouth
  • Stupor
  • Swelling of face, ankles, or hands
  • Swollen or painful glands
  • Unusual bleeding or bruising
  • Upper right abdominal or stomach pain
  • Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose
  • Anxiety
  • Blurred vision
  • Cold sweats
  • Cool, pale skin
  • Increased hunger
  • Nightmares
  • Shakiness
  • Slurred speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Lack or loss of strength
Incidence not known
  • Redness or other discoloration of the skin
  • Severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR602755 Portions of this document last updated: Sept. 1, 2012

Source: Drug Information provided by: Micromedex

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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