Ciprofloxacin (Intravenous Route)

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Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ciprofloxacin injection in children. However, because of this medicine's toxicity, it should be used with caution, after other alternatives have been considered and/or found ineffective. Ciprofloxacin injection may be used in children to prevent anthrax infection after possible exposure, and to treat serious kidney infections.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ciprofloxacin injection in the elderly. However, elderly patients are more likely to have age-related heart or kidney problems, or develop severe tendon problems (including tendon rupture), which may require caution in patients receiving ciprofloxacin injection.

Pregnancy

Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Cisapride
• Dronedarone
• Mesoridazine
• Pimozide
• Sparfloxacin
• Thioridazine
• Tizanidine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acarbose
• Acecainide
• Acetohexamide
• Alfuzosin
• Alosetron
• Amiodarone
• Amitriptyline
• Amoxapine
• Apomorphine
• Arsenic Trioxide
• Asenapine
• Astemizole
• Azimilide
• Azithromycin
• Bendamustine
• Benfluorex
• Bretylium
• Chlorpromazine
• Chlorpropamide
• Citalopram
• Clarithromycin
• Clomipramine
• Crizotinib
• Dasatinib
• Desipramine
• Disopyramide
• Dofetilide
• Dolasetron
• Domperidone
• Droperidol
• Eltrombopag
• Erythromycin
• Fingolimod
• Flecainide
• Fluconazole
• Gatifloxacin
• Gemifloxacin
• Gliclazide
• Glimepiride
• Glipizide
• Gliquidone
• Glyburide
• Granisetron
• Guar Gum
• Halofantrine
• Haloperidol
• Ibutilide
• Iloperidone
• Imipramine
• Insulin
• Insulin Aspart, Recombinant
• Insulin Glulisine
• Insulin Lispro, Recombinant
• Lapatinib
• Levofloxacin
• Lopinavir
• Lumefantrine
• Mefloquine
• Metformin
• Methadone
• Mifepristone
• Miglitol
• Moricizine
• Moxifloxacin
• Nilotinib
• Norfloxacin
• Nortriptyline
• Octreotide
• Ofloxacin
• Ondansetron
• Paliperidone
• Pazopanib
• Perflutren Lipid Microsphere
• Posaconazole
• Procainamide
• Prochlorperazine
• Promethazine
• Propafenone
• Protriptyline
• Quetiapine
• Quinidine
• Quinine
• Ranolazine
• Salmeterol
• Saquinavir
• Sematilide
• Simvastatin
• Sodium Phosphate
• Sodium Phosphate, Dibasic
• Sodium Phosphate, Monobasic
• Solifenacin
• Sorafenib
• Sotalol
• Sunitinib
• Tedisamil
• Telavancin
• Telithromycin
• Terfenadine
• Tetrabenazine
• Theophylline
• Tolazamide
• Tolbutamide
• Toremifene
• Trazodone
• Trifluoperazine
• Trimipramine
• Troglitazone
• Vandetanib
• Vardenafil
• Vemurafenib
• Voriconazole
• Warfarin
• Ziprasidone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Betamethasone
• Chloroquine
• Clozapine
• Corticotropin
• Cortisone
• Cosyntropin
• Cyclosporine
• Deflazacort
• Dexamethasone
• Diclofenac
• Dutasteride
• Erlotinib
• Fludrocortisone
• Fluocortolone
• Fosphenytoin
• Hydrocortisone
• Itraconazole
• Methylprednisolone
• Mycophenolate Mofetil
• Olanzapine
• Paramethasone
• Phenytoin
• Prednisolone
• Prednisone
• Probenecid
• Rasagiline
• Rifapentine
• Ropinirole
• Ropivacaine
• Sildenafil
• Triamcinolone
• Zolpidem

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Caffeine

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Brain or spinal cord disease, including hardening of the arteries in the brain or epilepsy or other seizures or
• Diabetes or
• Diarrhea or
• Heart rhythm problems (e.g., prolonged QT interval) or
• Hypokalemia (low potassium in the blood), uncorrected—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of this medicine from the body.

• Myasthenia gravis (severe muscle weakness)—Should not be used in patients with this condition.

• Organ transplant (e.g., kidney, heart, or lung) or
• Tendon disorder (e.g., rheumatoid arthritis), history of—Use with caution. May increase the risk of tendon problems.

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