Romiplostim (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Black, tarry stools
• Bleeding gums
• Blood in the urine or stools
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Difficulty with breathing
• Pain in the chest, groin, or legs, especially the calves
• Pinpoint red spots on the skin
• Severe, sudden headache
• Slurred speech
• Sudden loss of coordination
• Sudden, severe weakness or numbness in the arm or leg
• Sudden, unexplained shortness of breath
• Unusual bleeding or bruising
• Vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Difficulty with moving
• Dizziness
• Headache
• Heartburn
• Indigestion
• Muscle aching or cramping
• Muscle pains or stiffness
• Pain in the arms or legs
• Pain in the joints
• Pain in the shoulder
• Sleeplessness
• Stomach discomfort, upset, or pain
• Swollen joints
• Trouble sleeping
• Unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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