Nilutamide (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blood in the urine
• Blurred vision
• Chest pain
• Chills
• Cough
• Diarrhea
• Difficult or labored breathing
• Dizziness
• Fever or chills
• General feeling of discomfort or illness
• Headache
• Joint pain
• Loss of appetite
• Muscle aches and pains
• Nausea
• Nervousness
• Pale skin
• Pounding in the ears
• Runny nose
• Shivering
• Shortness of breath
• Slow or fast heartbeat
• Sneezing
• Sore throat
• Sweating
• Tightness in the chest
• Trouble with sleeping
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Vomiting
• Wheezing

• Arm, back, or jaw pain
• Blindness
• Bloody, black, or tarry stools
• Change in color vision
• Decreased urine output
• Decreased vision
• Difficulty seeing at night
• Dilated neck veins
• Fainting
• Fast or irregular heartbeat
• Increased cough
• Increased sensitivity of the eyes to sunlight
• Irregular breathing
• Swelling of the face, fingers, feet, or lower legs
• Vomiting of blood or material that looks like coffee grounds
• Weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Body hair loss
• Bone pain
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Changes in vision
• Decrease in testicle size
• Decreased interest in sexual intercourse
• Depression
• Difficulty having a bowel movement (stool)
• Dizziness
• Dry skin
• Feeling of warmth
• Heartburn
• Inability to have or keep an erection
• Increased urge to urinate during the night
• Indigestion
• Loss in sexual ability, desire, drive, or performance
• Pain
• Rash
• Redness of the face, neck, arms and occasionally, upper chest
• Sleeplessness
• Stomach discomfort, upset, or pain
• Sudden sweating
• Unable to sleep
• Waking to urinate at night

• Difficulty with moving
• Dry mouth
• General feeling of discomfort or illness
• Itching
• Muscle pain or stiffness
• Pain, swelling, or redness in the joints
• Passing of gas

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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