Adapalene and Benzoyl Peroxide (Topical Application Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Dryness and peeling of the skin
• Flushing or redness of the skin
• Unusually warm skin

• Blistering, burning, crusting, or flaking of the skin
• Burning, itching, redness, skin rash, swelling, or soreness at the application site
• Scaling, severe redness, or swelling of the skin

• Pain of the skin
• Sunburn

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Burning, dry, or itching eyes
• Change in the color of the treated skin
• Discharge or excessive tearing
• Redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
• Skin rash, encrusted, scaly, and oozing
• Swelling of the face

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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