Tapentadol (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Bladder pain
  • Bloody or cloudy urine
  • Body aches or pain
  • Chills
  • Cough
  • Difficult, burning, or painful urination
  • Difficulty in breathing
  • Ear congestion
  • Fever
  • Frequent urge to urinate
  • Headache
  • Loss of voice
  • Lower back or side pain
  • Muscle aches
  • Nasal congestion
  • Runny nose
  • Sneezing
  • Sore throat
  • Stuffy or runny nose
  • Unusual tiredness or weakness
Rare
  • Anxiety
  • Being forgetful
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • Changes in patterns and rhythms of speech
  • Clumsiness or unsteadiness
  • Confusion
  • Confusion about identity, place, and time
  • Convulsions
  • Delusions
  • Dementia
  • Drowsiness
  • Dry mouth
  • Fainting
  • False or unusual sense of well-being
  • Fast heartbeat
  • Feeling drunk
  • Hives
  • Hoarseness
  • Hyperventilation
  • Irregular heartbeats
  • Irregular, fast, slow, or shallow breathing
  • Irritability
  • Itching
  • Joint pain, stiffness, or swelling
  • Nervousness
  • Pale or blue lips, fingernails, or skin
  • Rash
  • Redness of the skin
  • Relaxed and calm
  • Restlessness
  • Sensation of heaviness
  • Shakiness and unsteady walk
  • Shortness of breath
  • Sleepiness
  • Slurred speech
  • Swelling
  • Swelling of the eyelids, face, lips, hands, or feet
  • Tightness in the chest
  • Trouble in speaking
  • Trouble with sleeping
  • Troubled breathing or swallowing
  • Unsteadiness, trembling, or other problems with muscle control or coordination
  • Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Constipation
  • Dizziness
  • Nausea
  • Sleepiness or unusual drowsiness
  • Vomiting
Less common
  • Abnormal dreams
  • Acid or sour stomach
  • Belching
  • Decreased appetite
  • Difficulty in moving
  • Feeling hot
  • Feeling of warmth
  • Heartburn
  • Increased sweating
  • Indigestion
  • Muscle pain or stiffness
  • Rash
  • Redness of the face, neck, arms, and occasionally, upper chest
  • Sleeplessness
  • Stomach discomfort, upset, or pain
  • Sudden sweating
  • Unable to sleep
  • Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Rare
  • Blurred or loss of vision
  • Disturbed color perception
  • Double vision
  • Halos around lights
  • Night blindness
  • Overbright appearance of lights
  • Tunnel vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR602877 Portions of this document last updated: Nov. 1, 2011

Source: Drug Information provided by: Micromedex

Copyright © 2012 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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