Temozolomide (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Bladder pain
  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • Bloody or cloudy urine
  • Body aches or pain
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • Chills
  • Cold flu-like symptoms
  • Congestion
  • Cough or hoarseness
  • Difficult, burning, or painful urination
  • Difficulty with breathing
  • Dryness or soreness of the throat
  • Ear congestion
  • Fever
  • Frequent urge to urinate
  • Headache
  • Loss of ability to use or understand speech or language
  • Loss of bladder control
  • Loss of voice
  • Lower back or side pain
  • Nasal congestion
  • Pain or tenderness around the eyes and cheekbones
  • Partial or slight paralysis
  • Rapid weight gain
  • Seizures
  • Shakiness and unsteady walk
  • Shortness of breath or troubled breathing
  • Sneezing
  • Sore throat
  • Stuffy or runny nose
  • Tender, swollen glands in the neck
  • Tightness of the chest or wheezing
  • Tingling of the hands or feet
  • Trouble with swallowing
  • Unsteadiness, trembling, or other problems with muscle control or coordination
  • Unusual tiredness or weakness
  • Unusual weight gain or loss
  • Voice changes
Less common
  • Black, tarry stools
  • Bleeding gums
  • Dizziness
  • Fast heartbeat
  • Flushing, redness of the skin
  • Hives
  • Itching
  • Pinpoint red spots on the skin
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Skin rash
  • Unusual bleeding or bruising
  • Unusually warm skin
Incidence not known
  • Deep, dark purple bruise
  • Itching, pain, redness, or swelling
  • Small red or purple spots on the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach pain
  • Back pain
  • Being forgetful
  • Blurred vision
  • Breast pain
  • Change in walking and balance
  • Clumsiness or unsteadiness
  • Constipation
  • Discouragement
  • Dizziness
  • Fear or nervousness
  • Feeling sad or empty
  • Hair loss or thinning of the hair
  • Irritability
  • Itching skin
  • Lack or loss of strength
  • Loss of appetite
  • Loss of interest or pleasure
  • Loss of memory
  • Nausea or vomiting
  • Problems with memory
  • Sleepiness or unusual drowsiness
  • Sleeplessness
  • Tiredness
  • Trouble concentrating
  • Trouble sleeping
  • Unable to sleep
  • Weight loss
Less common
  • Change in taste or bad unusual or unpleasant (after) taste
  • Changes in vision
  • Difficulty with moving
  • Double vision
  • Dry skin
  • Increased weight
  • Joint pain
  • Mood or mental changes
  • Muscle aching or cramping
  • Muscle pains or stiffness
  • Seeing double
  • Swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR602887 Portions of this document last updated: Nov. 1, 2011

Source: Drug Information provided by: Micromedex

Copyright © 2012 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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