Lidocaine and Tetracaine (Topical Application Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Flushing or redness of the skin
• Swelling
• Unusually warm skin

• Blistering, burning, crusting, dryness, or flaking of the skin
• Change in the color of treated skin
• Itching, scaling, severe redness, soreness, or swelling of the skin
• Rash

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Cough or hoarseness
• Fainting or loss of consciousness
• Fast or irregular breathing
• Fever or chills
• Hives or welts
• Lower back or side pain
• Painful or difficult urination
• Swelling of the eyes or eyelids
• Tightness in the chest or wheezing
• Trouble with breathing

• Blurred vision
• Chest pain or discomfort
• Cold, clammy, or pale skin
• Confusion
• Difficulty with breathing
• Difficulty with swallowing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• Fast, slow, or irregular heartbeat
• Feelings of coldness, heat, or numbness
• Irregular, fast or slow, or shallow breathing
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• No breathing
• Noisy breathing
• Pale or blue lips, fingernails, or skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Seizures
• Shakiness in the legs, arms, hands, or feet
• Shortness of breath
• Slow heart rate
• Sweating
• Trembling or shaking of the hands or feet
• Twitching
• Unconsciousness
• Unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

• Change in consciousness
• Fast, pounding, or irregular heartbeat or pulse
• No blood pressure or pulse
• Stopping of heart

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Headache
• Nausea
• Sleepiness or unusual drowsiness
• Vomiting

• Continuing ringing or buzzing or other unexplained noise in the ears
• Depression
• Double vision
• Drowsiness
• False or unusual sense of well-being
• Fear
• Hearing loss
• Nervousness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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