Nitroglycerin (Oral Route, Sublingual Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Difficult or labored breathing
• Feeling faint, dizzy, or lightheadedness
• Feeling of warmth or heat
• Flushing or redness of the skin, especially on the face and neck
• Headache
• Rapid weight gain
• Shortness of breath
• Sweating
• Tightness in the chest
• Tingling of the hands or feet
• Unusual weight gain or loss
• Wheezing

• Bluish-colored lips, fingernails, or palms
• Dark urine
• Fever
• Pale skin
• Rapid heart rate
• Sore throat
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Arm, back, or jaw pain
• Blurred vision
• Chest pain or discomfort
• Chest tightness or heaviness
• Confusion
• Cough
• Cracks in the skin
• Difficulty with swallowing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Fast, irregular, pounding, or racing heartbeat or pulse
• Feeling of constant movement of self or surroundings
• Feeling of warmth
• Hives
• Increased sweating
• Itching
• Loss of heat from the body
• Nausea or vomiting
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rash
• Red, swollen skin
• Redness of the face, neck, arms, and occasionally, upper chest
• Scaly skin
• Sensation of spinning
• Skin rash
• Weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

• Blurred or loss of vision
• Bulging soft spot on the head of an infant
• Change in consciousness
• Change in the ability to see colors, especially blue or yellow
• Cold, clammy skin
• Disturbed color perception
• Double vision
• Flushed skin
• Halos around lights
• Headache, severe and throbbing
• Increased sweating
• Loss of appetite
• Loss of consciousness
• Night blindness
• Overbright appearance of lights
• Paralysis
• Slow or irregular heartbeat
• Tunnel vision

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach pain
• Body aches or pain
• Congestion
• Hoarseness
• Lack or loss of strength
• Runny nose
• Sneezing
• Stuffy nose
• Tender, swollen glands in the neck
• Voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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