Methimazole (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Black, tarry stools
• Chest pain
• Chills
• Cough
• Fever
• Painful or difficult urination
• Shortness of breath
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Swollen glands
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Backache
• Increase or decrease in urination
• Swelling of the feet or lower legs

• Abdominal or stomach pain
• Bleeding gums
• Bleeding under the skin
• Blood in the urine or stools
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Cough or hoarseness
• Dark urine
• Difficulty with moving
• Fever with or without chills
• General feeling of discomfort, illness, or weakness
• General feeling of tiredness or weakness
• Headache
• Joint pain
• Light-colored stools
• Loss of appetite and weight
• Lower back or side pain
• Muscle aching or cramping
• Muscle pain or stiffness
• Nausea and vomiting
• Numbness or tingling of the hands, feet, or face
• Pinpoint red spots on the skin
• Soreness of the muscles
• Sores, ulcers, or white spots on the lips or in the mouth
• Swollen joints
• Swollen salivary glands
• Swollen, painful, or tender lymph glands in the neck, armpit, or groin
• Tightness in the chest
• Upper right abdominal pain
• Wheezing
• Yellow eyes and skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Cloudy or bloody urine
• Cracks in the skin
• High blood pressure
• Loss of heat from the body
• Red, swollen skin
• Scaly skin
• Sensation of pins and needles
• Stabbing pain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abnormal loss of hair
• Dizziness or lightheadedness
• Feeling of constant movement of self or surroundings
• Heartburn
• Hives or welts
• Itching
• Loss of taste
• Pain or discomfort in the chest, upper stomach, or throat
• Redness of the skin
• Sensation of spinning
• Skin rash
• Sleepiness
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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