Risperidone (Intramuscular Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Difficulty with swallowing
• Drowsiness
• Inability to sit still
• Loss of balance control
• Mask-like face
• Need to keep moving
• Relaxed and calm
• Restlessness
• Shuffling walk
• Sleepiness
• Slowed movements
• Slurred speech
• Stiffness of the arms and legs
• Tic-like (jerky) movements of the head, face, mouth, and neck
• Trembling and shaking of the fingers and hands

• Abdominal or stomach pain
• Abnormal or decreased touch sensation
• Absence of or decrease in body movement
• Anxiety
• Back pain
• Black, tarry, stools
• Bladder pain
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Bloody or cloudy urine
• Blurred vision
• Body aches or pain
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Change in walking and balance
• Changes in patterns and rhythms of speech
• Chest pain or discomfort
• Clumsiness or unsteadiness
• Cold flu-like symptoms
• Cold sweats
• Convulsions
• Cough or hoarseness
• Cough producing mucus
• Depression
• Diarrhea
• Difficult or labored breathing
• Difficult, burning, or painful urination
• Difficulty with breathing
• Difficulty with moving
• Disturbed attention
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up from lying or sitting position
• Dry mouth
• Ear congestion
• Fainting
• Fast, irregular, pounding, or racing heartbeat or pulse
• Fever or chills
• Flushed, dry skin
• Frequent urge to urinate
• Fruit-like breath odor
• General feeling of discomfort or illness
• Hard lump
• Headache
• Hyperventilation
• Inability to move the eyes
• Increased blinking or spasms of the eyelid
• Increased hunger
• Increased thirst
• Increased urination
• Irritability
• Joint pain
• Lip smacking or puckering
• Loss of appetite
• Loss of bladder control
• Loss of voice
• Lower back or side pain
• Muscle aches and pains
• Muscle stiffness
• Muscle weakness
• Nasal congestion
• Nausea
• Neck pain
• Pain
• Pale skin
• Pounding in the ears
• Pounding, slow heartbeat
• Puffing of the cheeks
• Rapid or worm-like movements of the tongue
• Rapid weight gain
• Shivering
• Shortness of breath
• Slow or fast heartbeat
• Sneezing
• Sore throat
• Sticking out of the tongue
• Stuffy or runny nose
• Sweating
• Swelling or puffiness of the face
• Swollen joints
• Tightness in the chest
• Trouble with breathing, speaking, or swallowing
• Trouble with sleeping
• Troubled breathing with exertion
• Ulcers, sores, or white spots in the mouth
• Uncontrolled chewing movements
• Uncontrolled twisting movements of the neck, trunk, arms, or legs
• Unexplained weight loss
• Unusual bleeding or bruising
• Unusual facial expressions
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Vomiting
• Wheezing

• Abnormal growth filled with fluid or semisolid material
• Accumulation of pus
• Actions that are out of control
• Bleeding gums
• Blood in the urine or stools
• Bluish lips or skin
• Break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid
• Change in vision
• Clay-colored stools
• Clumsiness
• Collection of blood under the skin
• Coma
• Confusion
• Constipation
• Dark urine
• Deep, dark purple bruise
• Drowsiness
• Fever with or without chills
• Flushed, dry skin
• Fruit-like breath odor
• Indigestion
• Itching
• Itching, pain, redness, or swelling
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of consciousness
• Low body temperature
• Not breathing
• Painful or prolonged erection of the penis
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pinpoint red spots on the skin
• Rash
• Severe constipation
• Swollen, red, tender area of infection
• Talking, feeling, and acting with excitement
• Tiredness
• Unexplained weight loss
• Unpleasant breath odor
• Vomiting of blood
• Weak or feeble pulse
• Weight gain
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Heartburn
• Stomach discomfort, upset, or pain

• Abnormal ejaculation
• Absent missed or irregular menstrual periods
• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Blemishes on the skin
• Burning, dry, or itching eyes
• Change in hearing
• Decreased interest in sexual intercourse
• Decreased sexual performance or desire
• Decreased vision
• Discharge, excessive tearing
• Dry skin
• Ear drainage
• Ear pain
• Feeling of constant movement of self or surroundings
• Inability to have or keep an erection
• Increased watering of the mouth
• Loss in sexual ability, desire, drive, or performance
• Pain or tenderness around the eyes and cheekbones
• Pimples
• Redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
• Sensation of spinning
• Skin rash, encrusted, scaly and oozing
• Sleeplessness
• Sluggishness
• Stopping of menstrual bleeding
• Swelling of the breasts or unusual milk production
• Swelling of the breasts or breast soreness in both females and males
• Tender, swollen glands in the neck
• Tenderness in the stomach area
• Toothache
• Unable to sleep
• Unexpected or excess milk flow from breasts
• Voice changes
• Weight gain
• Weight loss

• Hair loss or thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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