Colistimethate (Injection Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Blood in the urine
• Bluish lips or skin
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Change in frequency of urination or amount of urine
• Decrease in amount of urine
• Difficulty with breathing
• Drowsiness
• Fever
• Increased thirst
• Loss of appetite
• Nausea or vomiting
• Shortness of breath
• Slurred speech
• Swelling of the feet or lower legs
• Tightness in the chest
• Tingling of the arms, legs, and tongue
• Troubled breathing
• Weakness
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Dizziness
• Mood or mental changes
• Shakiness and unsteady walk
• Uncontrolled eye movements
• Unsteadiness, trembling, or other problems with muscle control or coordination
• Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Diarrhea
• Dizziness or lightheadedness
• Feeling of constant movement of self or surroundings
• Hives or welts
• Itching
• Redness of the skin
• Sensation of spinning
• Stomach cramps or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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