Telmisartan and Amlodipine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Body aches or pain
• Chills
• Cough
• Difficulty with breathing
• Ear congestion
• Fever
• Headache
• Loss of voice
• Nasal congestion
• Rapid weight gain
• Runny nose
• Sneezing
• Sore throat
• Tingling of the hands or feet
• Unusual tiredness or weakness
• Unusual weight gain or loss

• Bladder pain
• Bloody or cloudy urine
• Blurred vision
• Chest pain
• Diarrhea
• Difficult, burning, or painful urination
• Dizziness
• Frequent urge to urinate
• General feeling of discomfort or illness
• Joint pain
• Loss of appetite
• Lower back or side pain
• Muscle aches and pains
• Nausea
• Nervousness
• Pounding in the ears
• Shivering
• Slow or fast heartbeat
• Sweating
• Trouble with sleeping
• Vomiting

• Abdominal or stomach pain
• Arm, back, or jaw pain
• Black, tarry stools
• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Blood in the urine or stools
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest tightness or heaviness
• Cold sweats
• Confusion
• Constipation
• Cough or hoarseness
• Dark urine
• Difficult or labored breathing
• Difficulty with swallowing
• Dilated neck veins
• Dry mouth
• Extreme fatigue
• Fast, irregular, pounding, or racing heartbeat or pulse
• Feeling of warmth
• Flushed, dry skin
• Fruit-like breath odor
• Hives
• Increased hunger
• Increased sweating
• Increased thirst
• Increased volume of pale, dilute urine
• Indigestion
• Irregular heartbeat
• Irritation in the mouth
• Joint or muscle pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Lightheadedness, dizziness, or fainting
• Loss of consciousness
• Muscle cramps or stiffness
• Pale, bluish-colored, or cold hands or feet
• Pinpoint red spots on the skin
• Rash
• Redness and swelling of the gums
• Redness, soreness, or itching skin
• Severe or sudden headache
• Sudden loss of coordination
• Sudden slurring of speech
• Swollen glands
• Tightness in the chest
• Trembling or shaking of the hands or feet
• Troubled breathing
• Unexplained weight loss
• Unsteadiness, trembling, or other problems with muscle control or coordination
• Unusual bleeding or bruising
• Vomiting of blood
• Waking to urinate at night
• Weakness in the arms, hands, legs, or feet
• Weight gain
• Yellow eyes or skin

• Decreased urine output
• Nervousness
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Weakness or heaviness of the legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Difficulty with moving
• Heartburn
• Indigestion
• Pain or tenderness around the eyes and cheekbones
• Sleepiness or unusual drowsiness

• Abnormal dreams
• Abnormal ejaculation
• Ankle, knee, or great toe joint pain
• Anxiety
• Bad, unusual, or unpleasant (after) taste
• Bleeding after defecation
• Blistering, crusting, irritation, itching, or reddening of the skin
• Bloody nose
• Burning feeling in the chest or stomach
• Burning, dry, or itching eyes
• Changes in vision
• Cold and clammy skin
• Continuing ringing or buzzing or other unexplained noise in the ears
• Cough producing mucus
• Cracked, dry, or scaly skin
• Decreased sexual performance or desire
• Depression
• Discharge or excessive tearing
• Dry mouth
• Dryness of the eyes
• Dryness of the skin
• Earache
• Excess air or gas in the stomach or intestines
• Feeling of constant movement of self or surroundings
• Feeling of unreality
• Feeling of warmth
• Full feeling
• Hair loss or thinning of the hair
• Headache, severe and throbbing
• Hearing loss
• Hives or welts
• Hyperventilation
• Inability to have or keep an erection
• Increased appetite
• Irritability
• Lack of feeling or emotion
• Lack or loss of strength
• Loose stools
• Loss of memory
• Pinpoint red or purple spots on the skin
• Redness of the face, neck, arms, and occasionally, upper chest
• Redness of the skin
• Redness or swelling in the ear
• Redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
• Restlessness
• Tenderness in the stomach area
• Toothache
• Unable to sleep
• Uncomfortable swelling around the anus

• Decreased interest in sexual intercourse
• Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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