Cefotaxime (Injection Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach cramps or tenderness
• Black, tarry stools
• Bloating
• Chest pain
• Chills
• Diarrhea
• Diarrhea, watery and severe, which may also be bloody
• Difficulty with breathing
• Difficulty with swallowing
• Dizziness
• Fast heartbeat
• Fever
• Hives
• Increased thirst
• Itching
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Nausea or vomiting
• Noisy breathing
• Pain
• Painful or difficult urination
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Shortness of breath
• Skin rash
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Swollen glands
• Tenderness
• Tightness in the chest
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Unusual weight loss
• Wheezing

• Agitation
• Back, leg, or stomach pains
• Bleeding gums
• Blistering, peeling, or loosening of the skin
• Blood in the urine or stools
• Bloody or cloudy urine
• Blurred vision
• Coma
• Confusion
• Cough or hoarseness
• Cracks in the skin at the corners of the mouth
• Dark urine
• Drowsiness
• Fainting
• Fast, slow, or irregular heartbeat
• Fever with or without chills
• General body swelling
• General feeling of tiredness or weakness
• Greatly decreased frequency of urination or amount of urine
• Hallucinations
• Headache
• Irritability
• Itching
• Itching of the vagina or genital area
• Joint or muscle pain
• Loss of appetite
• Lower back or side pain
• Mood or mental changes
• Nosebleeds
• Pain during sexual intercourse
• Pale skin
• Pinpoint red spots on the skin
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Seizures
• Soreness or redness around the fingernails and toenails
• Stiff neck
• Swelling of the feet or lower legs
• Thick, white vaginal discharge with no odor or with a mild odor
• Yellowing of the eyes or skin

• Clay-colored stools
• Unpleasant breath odor
• Vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Red streaks on the skin
• Swelling, tenderness, or pain at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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