Cefepime (Injection Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach cramps
• Back, leg, or stomach pains
• Bleeding gums
• Chills
• Confusion
• Convulsions
• Dark urine
• Difficulty with breathing
• Fever
• General body swelling
• Headache
• Irregular heartbeats
• Loss of appetite
• Mood or mental changes
• Muscle cramps in the hands, arms, feet, legs, or face
• Nausea or vomiting
• Nosebleeds
• Numbness and tingling around the mouth, fingertips, or feet
• Pale skin
• Shortness of breath
• Sore throat
• Tremor
• Yellowing of the eyes or skin

• Bluish color
• Changes in skin color
• Pain
• Swelling of the foot or leg
• Tenderness

• Diarrhea
• Inflammation or swelling
• Watery or bloody diarrhea

• Agitation
• Back pain
• Blistering, peeling, or loosening of the skin
• Blood in the urine or stools
• Bloody or cloudy urine
• Bloody, black, or tarry stools
• Blurred vision
• Change in consciousness
• Chest pain
• Clay-colored stools
• Cloudy urine
• Coma
• Cough or hoarseness
• Coughing up blood
• Decrease in urine output or decrease in urine-concentrating ability
• Decreased awareness or responsiveness
• Difficult or painful urination
• Difficulty with swallowing
• Dizziness
• Drowsiness
• Fast heartbeat
• Fever with or without chills
• General feeling of tiredness or weakness
• High fever
• Hives
• Increased menstrual flow or vaginal bleeding
• Irritability
• Itching
• Joint or muscle pain
• Loss of appetite
• Loss of consciousness
• Lower back or side pain
• Muscle twitching or jerking
• Nosebleeds
• Painful or difficult urination
• Pale skin
• Paralysis
• Pinpoint red spots on the skin
• Prolonged bleeding from cuts
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Red irritated eyes
• Red or black, tarry stools
• Red or dark brown urine
• Red skin lesions, often with a purple center
• Rhythmic movement of the muscles
• Seeing, hearing, or feeling things that are not there
• Seizures
• Severe sleepiness
• Shortness of breath
• Skin rash
• Sore throat
• Sores, ulcers, or white spots in the mouth or on the lips
• Stiff neck
• Sudden decrease in the amount of urine
• Swollen or painful glands
• Tightness in the chest
• Unpleasant breath odor
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Vomiting of blood
• Wheezing
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Red streaks on the skin
• Swelling, tenderness, or pain at the injection site

• Itching of the vagina or genital area
• Pain during sexual intercourse
• Redness of the skin
• Sore mouth or tongue
• Thick, white vaginal discharge with no odor or with a mild odor
• White patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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