Levonorgestrel (Intrauterine Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or pelvic pain
• Absent, missed, or irregular menstrual periods
• Longer or heavier menstrual periods
• Mild bloating
• Stopping of menstrual bleeding
• Unusually heavy or unexpected menstrual bleeding
• Uterine bleeding between menstrual periods
• Vaginal bleeding or spotting

• Blurred vision
• Cramps
• Dizziness
• Headache
• Heavy bleeding
• Itching of the vagina or genital area
• Itching of the vagina or genitals
• Nervousness
• Pain
• Pain during sexual intercourse
• Painful sexual intercourse
• Pale skin
• Pounding in the ears
• Slow or fast heartbeat
• Swelling
• Thick, white vaginal discharge with mild or no odor
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• White or brownish vaginal discharge

• Chills
• Confusion
• Dizziness, lightheadedness, or fainting
• Fast heartbeat
• Fast, weak pulse
• Fever
• Pale, cold, clammy skin
• Rapid, shallow breathing
• Sudden increase in stomach or shoulder pain
• Sweating
• Unusual or large amount of vaginal bleeding

• Clear or bloody discharge from nipple
• Dimpling of breast skin
• Dull or aching abdominal or stomach pain
• Foul-smelling vaginal discharge
• Increased urge to urinate
• Inverted nipple
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Lump in the breast or under the arm
• Pain on urination
• Persistent crusting or scaling of the nipple
• Redness or swelling of the breast
• Severe abdominal or stomach pain or cramping
• Sharp pain on insertion
• Shivering fever
• Sore on the skin of the breast that does not heal
• Unexpected, heavy vaginal bleeding

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Blemishes on the skin
• Depression
• Pimples

• Back pain
• Breast tenderness or pain
• Decreased interest in sexual intercourse
• Full or bloated feeling
• Hair loss
• Hives or welts
• Increased hair growth, especially on the face
• Increased weight
• Itching
• Loss in sexual ability, desire, drive, or performance
• Nausea
• Nervousness
• Pressure in the stomach
• Rash
• Redness of the skin
• Skin rash, encrusted, scaly, and oozing
• Swelling of the abdominal or stomach area
• Thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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