Testosterone (Topical Application Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blood in the urine
• Difficulty urinating
• Feeling need to urinate often
• Frequent urination

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blurred vision
• Dizziness
• Feeling faint, dizzy, or lightheaded
• Feeling of warmth or heat
• Flushing or redness of the skin, especially on the face and neck
• Frequent strong or increased urge to urinate
• Headache
• Increased urge to urinate during the night
• Nervousness
• Pain, redness, or swelling in the arm or leg
• Pounding in the ears
• Rapid weight gain
• Slow or fast heartbeat
• Sweating
• Swelling of the breasts or breast soreness in both females and males
• Tingling of the hands or feet
• Unusual weight gain or loss
• Waking to urinate at night

• Aggressive behavior
• Bluish lips or skin
• Decrease in testicle size
• Development of pubic hair
• Difficult or labored breathing
• Enlargement of the clitoris or penis
• Not breathing
• Painful or prolonged erection of the penis
• Shortness of breath
• Tightness in the chest
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Blemishes on the skin
• Burning, itching, redness, skin rash, swelling, or soreness at the application site
• Pimples

• Anxiety
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Crying
• Decreased interest in sexual intercourse
• Depersonalization
• Depression
• Discoloration of the hair
• Dry skin
• Dysphoria
• Euphoria
• Hair loss
• Inability to have or keep an erection
• Lack or loss of strength
• Loss in sexual ability, desire, drive, or performance
• Loss of memory
• Paranoia
• Problems with memory
• Quick to react or overreact emotionally
• Rapidly changing moods
• Thinning of the hair

• Increased in sexual ability, desire, drive, or performance
• Increased interest in sexual intercourse
• Sleeplessness
• Trouble with sleeping
• Unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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