Ofatumumab (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Black, tarry stools
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Body aches or pain
• Chest pain
• Chills
• Confusion
• Cough or hoarseness
• Cough producing mucus
• Difficult or labored breathing
• Dizziness
• Ear congestion
• Facial swelling
• Fainting
• Fast heartbeat
• Headache
• Increased sweating
• Lightheadedness
• Loss of voice
• Lower back or side pain
• Nasal congestion
• Nausea or vomiting
• Painful blisters on the trunk of the body
• Painful or difficult urination
• Pale skin
• Rapid weight gain
• Rapid, shallow breathing
• Runny nose
• Shortness of breath
• Skin rash
• Sneezing
• Sore throat
• Tightness in the chest
• Tingling of the hands or feet
• Troubled breathing
• Troubled breathing with exertion
• Ulcers, sores, or white spots in the mouth
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Weakness
• Wheezing

• Blurred vision
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fast, pounding, or irregular heartbeat or pulse
• Nervousness
• Pounding in the ears
• Slow or fast heartbeat
• Sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Hives or welts
• Itching
• Muscle aches
• Redness of the skin
• Sleeplessness
• Stuffy nose
• Trouble with sleeping
• Unable to sleep

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Muscle spasms
• Pain or tenderness around the eyes and cheekbones

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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