Clobetasol (Topical Application Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Burning or stinging at the application site

• Burning sensation of the skin
• Dry skin
• Flushing or redness of the skin
• Itching, scaling, severe redness, soreness, or swelling of the skin
• Skin irritation
• Skin rash, encrusted, scaly and oozing
• Thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)

• Burning, itching, and pain in hairy areas, or pus at the root of the hair
• Hair loss
• Redness and scaling around the mouth
• Thinning of the hair
• Thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Cough
• Sore throat

• Burning, itching, and pain in hairy areas, or pus at the root of the hair
• Changes in skin coloring
• Body aches or pain
• Congestion
• Cough
• Dryness or soreness of the throat
• Fever
• Headache
• Hoarseness
• Raised, dark red, wart-like spots on the skin, especially when used on the face
• Skin discomfort
• Stuffy or runny nose
• Tender, swollen glands in the neck
• Trouble with swallowing
• Unusual tiredness or weakness
• Voice changes

• Acne or pimples
• Burning and itching of the skin with pinhead-sized red blisters
• Increased hair growth on the forehead, back, arms, and legs
• Lightening of normal skin color
• Lightening of treated areas of dark skin
• Reddish purple lines on the arms, face, legs, trunk, or groin
• Softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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