Alendronate and Cholecalciferol (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Chest pain, discomfort, or burning
• Difficulty with swallowing
• Heartburn
• Muscle or bone pain
• Pain with swallowing
• Vomiting blood

• Abdominal or stomach cramps
• Blistering, peeling, or loosening of the skin
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Chills
• Confusion
• Convulsions
• Cough
• Diarrhea
• Difficulty with breathing
• Fever
• Irregular heartbeats
• Itching
• Joint pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Mood or mental changes
• Muscle cramps in the hands, arms, feet, legs, or face
• Numbness and tingling around the mouth, fingertips, or feet
• Rapid weight gain
• Red, irritated eyes
• Red skin lesions, often with a purple center
• Shortness of breath
• Sore throat
• Sores, ulcers, or white spots in the mouth or on the lips
• Swelling of the neck
• Tremor
• Troubled breathing
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Vomiting

• Burning upper abdominal or stomach pain
• Difficulty with moving
• Loss of appetite
• Muscle aching or cramping
• Muscle pains or stiffness
• Pain or burning in the throat
• Stomach bloating, burning, cramping, or pain
• Swollen joints
• Weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Belching
• Constipation
• Excess air or gas in the stomach or intestines
• Full feeling
• Full or bloated feeling
• Headache
• Indigestion
• Passing gas
• Pressure in the stomach
• Stomach discomfort, upset, or pain
• Swelling of the abdominal or stomach area

• Blurred vision or other change in vision
• Decreased vision
• Eye pain
• Eye redness
• Eye tenderness
• Flushing or redness of the skin
• Increased tearing
• Rash
• Redness of the eye
• Sensitivity of the eye to light
• Severe eye pain
• Tearing
• Unusually warm skin

• Dizziness or lightheadedness
• Feeling of constant movement of self or surroundings
• General feeling of discomfort or illness
• Hair loss
• Hives or welts
• Lack or loss of strength
• Sensation of spinning
• Thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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