Codeine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating
• Blurred vision
• Chills
• Cold, clammy skin
• Confusion
• Constipation
• Darkened urine
• Difficult or troubled breathing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Fast, irregular, pounding, or racing heartbeat or pulse
• Fast, weak pulse
• Feeling of warmth
• Fever
• Indigestion
• Irregular, fast or slow, or shallow breathing
• Lightheadedness
• Loss of appetite
• Nausea
• No blood pressure or pulse
• No breathing
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pale or blue lips, fingernails, or skin
• Redness of the face, neck, arms, and occasionally, upper chest
• Shortness of breath
• Stopping of the heart
• Sweating
• Unconsciousness
• Unusual tiredness or weakness
• Vomiting
• Wheezing
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Bluish lips or skin
• Change in consciousness
• Chest pain or discomfort
• Constricted, pinpoint, or small pupils (black part of the eye)
• Decreased awareness or responsiveness
• Extreme sleepiness or unusual drowsiness
• Loss of consciousness
• No blood pressure or pulse
• Severe sleepiness
• Slow or irregular heartbeat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Drowsiness
• Relaxed and calm

• Abdominal or stomach pain or cramps
• Blurred or loss of vision
• Diarrhea
• Disturbed color perception
• Double vision
• Dry mouth
• False or unusual sense of well-being
• Fear or nervousness
• Feeling of constant movement of self or surroundings
• Halos around lights
• Headache
• Hives or welts
• Itching skin
• Night blindness
• Overbright appearance of lights
• Redness of the skin
• Sensation of spinning
• Shakiness
• Skin rash
• Sleeplessness
• Trouble sleeping
• Tunnel vision
• Unable to sleep
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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