Levorphanol (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Agitation
• Attempts at killing oneself
• Bluish lips or skin
• Blurred vision
• Change in consciousness
• Cold, clammy skin
• Confusion
• Decrease in the frequency of urination
• Decrease in urine volume
• Decreased urine output
• Depression
• Difficulty in passing urine (dribbling)
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Extra heartbeats
• Extremely shallow or slow breathing
• Fast, slow, irregular, pounding, or racing heartbeat or pulse
• Fast, weak pulse
• Hostility
• Lethargy
• Lightheadedness
• Loss of consciousness
• Muscle twitching
• No blood pressure or pulse
• Not breathing
• Painful urination
• Rapid weight gain
• Seizures
• Stopping of the heart
• Stupor
• Sweating
• Swelling of the face, ankles, or hands
• Unconsciousness
• Unusual tiredness or weakness
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Chest pain or discomfort
• Constricted, pinpoint, or small pupils (black part of the eye)
• Decreased awareness or responsiveness
• Difficult or troubled breathing
• Difficulty with sleeping
• Dilated neck veins
• Disorientation
• Drowsiness to profound coma
• Extreme fatigue
• Hallucination
• Headache
• Irregular, fast or slow, or shallow breathing
• No muscle tone or movement
• Not breathing
• Pale or blue lips, fingernails, or skin
• Shortness of breath
• Sleepiness or unusual drowsiness
• Swelling of the face, fingers, feet, or lower legs
• Weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abnormal dreams
• Absence of or decrease in body movement
• Acid or sour stomach
• Belching
• Change in personality
• Changes in vision
• Delusions
• Dementia
• Discouragement
• Double vision
• Dry mouth
• Feeling sad or empty
• Heartburn
• Hives or welts
• Increase in body movements
• Indigestion
• Irritability
• Itching
• Lack of appetite
• Loss of interest or pleasure
• Loss of memory
• Nausea
• Nervousness
• Problems with memory
• Redness of the skin
• Seeing double
• Skin rash
• Stomach discomfort, upset, or pain
• Sweating
• Tiredness
• Trouble concentrating
• Trouble sleeping
• Twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
• Upper abdominal or stomach pain
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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