Polidocanol (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Collection of blood under the skin of the injection site
• Deep, dark purple bruise at the injection site

• Anxiety
• Blue-green to black skin discoloration
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Chest pain
• Cough
• Darkening of the skin
• Difficult or labored breathing
• Difficulty with swallowing
• Dizziness or lightheadedness
• Fainting
• Fast, irregular, pounding, or racing heartbeat or pulse
• Fever
• Inability to speak
• Increased hair growth in the treatment area
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of consciousness
• Nerve injury
• No blood pressure or pulse
• Noisy breathing
• Pain, redness, or sloughing of the skin at the injection site
• Pain, redness, or swelling in the arm or leg
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Seizures
• Severe or sudden headache
• Shortness of breath
• Skin rash
• Slurred speech
• Sores, welting, or blisters
• Stopping of the heart
• Sudden shortness of breath or troubled breathing
• Temporary blindness
• Tightness in the chest
• Unconsciousness
• Unusual tiredness or weakness
• Weakness in the arm or leg on one side of the body, sudden and severe
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Confusion
• Feeling of warmth
• Redness of the face, neck, arms, and occasionally, upper chest
• Sudden sweating

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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