Dihydrocodeine, Aspirin, and Caffeine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal pain, cramping, or tenderness
• Bleeding gums
• Blood in the urine or stools
• Bloody, black, or tarry stools
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Constipation
• Convulsions
• Coughing or vomiting blood
• Dark-colored urine
• Heartburn
• Hives or itching
• Increased menstrual flow or vaginal bleeding
• Indigestion
• Large, flat, blue or purplish patches in the skin
• Nausea or vomiting
• Nosebleeds
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pinpoint red or purple spots on the skin
• Prolonged bleeding from cuts
• Red or black, tarry stools or dark urine
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Vomiting of material that looks like coffee grounds, severe and continuing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Difficulty having a bowel movement (stool)
• Dizziness
• Drowsiness
• Itching skin
• Lightheadedness
• Nausea
• Relaxed and calm feeling
• Sleepiness
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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