Pentazocine and Naloxone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Black, tarry stools
  • Chest pain
  • Chills
  • Cough or hoarseness
  • Difficult or troubled breathing
  • Fever
  • Fever with or without chills
  • General feeling of tiredness or weakness
  • Irregular, fast or slow, or shallow breathing
  • Lower back or side pain
  • Painful or difficult urination
  • Pale or blue lips, fingernails, or skin
  • Shakiness in the legs, arms, hands, or feet
  • Shortness of breath
  • Sore throat
  • Sores, ulcers, or white spots on the lips or in the mouth
  • Swollen glands
  • Trembling or shaking of the hands or feet
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
Incidence not known
  • Blistering, peeling, or loosening of the skin
  • Blurred vision
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • Confusion
  • Decrease in the frequency of urination
  • Diarrhea
  • Difficulty in passing urine (dribbling)
  • Difficulty with swallowing
  • Dizziness
  • Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Fainting
  • Fast, slow, pounding, or irregular heartbeat or pulse
  • Feeling of warmth
  • Headache
  • Hives
  • Itching
  • Joint or muscle pain
  • Loss of bladder control
  • Loss of consciousness
  • Nervousness
  • Pounding in the ears
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Rapid breathing
  • Red skin lesions, often with a purple center
  • Red, irritated eyes
  • Redness of the face, neck, arms, and occasionally, upper chest
  • Skin rash
  • Sweating
  • Swelling of the lower legs or arms
  • Swelling of the face
  • Tightness in the chest
  • Total body jerking
  • Upper abdominal or stomach pain
  • Weight gain
  • Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose
  • Seeing, hearing, or feeling things that are not there
  • Seizures (convulsions)
  • Sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare
  • Abdominal or stomach distress
  • Hives or welts
  • Redness of the skin
Incidence not known
  • Blistering, crusting, irritation, itching, or reddening of the skin
  • Confusion about identity, place, and time
  • Constipation
  • Constricted, pinpoint, or small pupils (black part of the eye)
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • Cracked, dry, or scaly skin
  • Depression
  • Difficulty in focusing the eyes
  • Disturbed dreams
  • Drowsiness
  • Dry mouth
  • Excitement
  • False or unusual sense of well-being
  • Hearing loss
  • Irritability
  • Lightheadedness
  • Loss of appetite
  • Mood or mental changes
  • Nausea
  • Relaxed and calm feeling
  • Trouble with sleeping
  • Unable to sleep
  • Vomiting
  • Weakness
  • Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Precautions
DR603241 Portions of this document last updated: Dec. 1, 2012

Source: Drug Information provided by: Micromedex

Copyright © 2013 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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