Meperidine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blurred vision
• Chest pain or discomfort
• Cold, clammy skin
• Confusion
• Convulsion
• Cough
• Decrease in the frequency of urination
• Decrease in urine volume
• Difficult or troubled breathing
• Difficulty in passing urine (dribbling)
• Difficulty with swallowing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Fast, slow, pounding, or irregular heartbeat or pulse
• Fast, weak pulse
• Feeling of warmth
• Hives
• Irregular, fast, slow, or shallow breathing
• Itching
• Lightheadedness, dizziness, or fainting
• Muscle twitching or jerking
• Painful urination
• Pale or blue lips, fingernails, or skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Redness of the face, neck, arms, and occasionally, upper chest
• Rhythmic movement of the muscles
• Shakiness in the legs, arms, hands, or feet
• Shortness of breath
• Skin rash
• Sweating
• Tightness in the chest
• Trembling or shaking of the hands or feet
• Unconsciousness
• Unusual tiredness or weakness
• Upper abdominal or stomach pain
• Very low blood pressure or pulse
• Very slow breathing
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Bluish color of the fingernails, lips, skin, palms, or nail beds
• Change in consciousness
• Decreased awareness or responsiveness
• Loss of consciousness
• Severe sleepiness
• Sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Drowsiness
• Nausea
• Relaxed and calm
• Vomiting

• Anxiety
• Blurred or loss of vision
• Confusion about identity, place, and time
• Difficulty having a bowel movement (stool)
• Disturbed color perception
• Double vision
• Dry mouth
• False or unusual sense of well-being
• Halos around lights
• Headache
• Hives or welts
• Hyperventilation
• Irritability
• Nervousness
• Night blindness
• Overbright appearance of lights
• Redness of the skin
• Restlessness
• Seeing, hearing, or feeling things that are not there
• Trouble with sleeping
• Tunnel vision
• Weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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