Hydromorphone (Injection Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Blurred vision
• Change in the ability to see colors, especially blue or yellow
• Chest pain or discomfort
• Cold, clammy skin
• Confusion
• Cough
• Difficult or troubled breathing
• Dizziness
• Fast, pounding, or irregular heartbeat or pulse
• Fast or weak pulse
• Headache
• Irregular, fast, slow, or shallow breathing
• Lightheadedness, dizziness, or fainting
• Loss of appetite
• Low blood pressure
• Noisy breathing
• Pale or blue lips, fingernails, or skin
• Severe constipation
• Severe vomiting
• Shortness of breath
• Sleeplessness
• Slow or irregular heartbeat
• Sweating
• Tightness in the chest
• Trouble with sleeping
• Unable to sleep
• Unconscious
• Unusual tiredness
• Very slow breathing
• Very slow heartbeat or pulse
• Vomiting
• Wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

• Bigger, dilated, or enlarged pupils (black part of the eye)
• Decreased awareness or responsiveness
• Increased sensitivity of the eyes to light
• No muscle tone or movement
• Sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Anxiety
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Bad, unusual, or unpleasant (after) taste
• Change in taste
• Chills
• Constricted, pinpoint, or small pupils (black part of the eye)
• Decrease in the frequency of urination
• Decrease in urine volume
• Diarrhea
• Difficulty having a bowel movement (stool)
• Difficulty in passing urine (dribbling)
• Double vision
• Dry mouth
• False or unusual sense of well-being
• Feeling of warmth
• Hives or welts
• Hyperventilation
• Irritability
• Loss of appetite
• Muscle stiffness or tightness
• Nausea
• Painful urination
• Redness, pain, or swelling at the injection site
• Redness of the face, neck, arms, and occasionally, upper chest
• Relaxed and calm
• Seeing, hearing, or feeling things that are not there
• Seeing double
• Shaking
• Skin itching
• Sleepiness
• Uncontrolled eye movements
• Upper abdominal or stomach pain
• Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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