Sumatriptan (Subcutaneous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Blurred vision
• Chest pain or discomfort
• Chills
• Confusion
• Difficult or labored breathing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Fast, pounding, or irregular heartbeat or pulse
• Headache
• Nervousness
• Pounding in the ears
• Shakiness in the legs, arms, hands, or feet
• Shortness of breath
• Slow or fast heartbeat
• Sweating
• Tight feeling in the head
• Tightness or pressure in the chest
• Trembling or shaking of the hands or feet
• Unusual tiredness or weakness
• Wheezing

• Black, tarry stools
• Blood in the urine
• Blood in the vomit
• Burning while urinating
• Cough
• Decreased urination
• Depression of the skin
• Diarrhea
• Dry mouth
• Feeling of warmth or heat
• Fever
• Flushing or redness of the skin, especially on the face and neck
• General feeling of discomfort or illness
• Inability to move the eyes
• Inability to move the legs or arms
• Increase in heart rate
• Increased blinking or spasms of the eyelid
• Increased sensitivity to pain
• Increased sensitivity to touch
• Indentation of the skin
• Joint pain
• Loss of appetite
• Muscle aches and pains
• Nausea and vomiting
• Pain in the groin or genitals
• Paleness of the skin
• Paleness or cold feeling in the fingertips and toes
• Paralysis of one side of the body
• Rapid breathing
• Runny nose
• Severe or continuing stomach pain
• Sharp back pain just below the ribs
• Shivering
• Sore throat
• Sticking out of the tongue
• Sunken eyes
• Thirst
• Tingling in the hands and feet
• Tingling or pain in the fingers or toes when exposed to cold
• Trouble with breathing, speaking, or swallowing
• Trouble with sleeping
• Uncontrolled twisting movements of the neck, trunk, arms, or legs
• Unusual facial expressions
• Wrinkled skin

• Abdominal or stomach pain and tenderness
• Agitation
• Back, leg, or stomach pains
• Bleeding gums
• Blood in the stools
• Bluish color of the fingernails, lips, skin, palms, or nail beds
• Changes in skin color
• Changes in vision
• Coma
• Depression
• Difficulty with swallowing
• Double vision
• General body swelling
• Headache, sudden, severe, and continuing
• High fever
• Hives
• Hostility
• Inability to speak
• Irritability
• Itching
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Lethargy
• Loss of ability to use or understand speech or language
• Loss of appetite
• Loss of vision
• Migraine headache
• Muscle twitching
• Noisy breathing
• Nosebleeds
• Overactive reflexes
• Pain, tenderness, or swelling of the foot or leg
• Pinpoint red spots on the skin
• Poor coordination
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rapid weight gain
• Rectal bleeding
• Redness, soreness, or itching skin
• Restlessness
• Seizures
• Severe or sudden headache
• Slurred speech
• Sores, ulcers, or white spots on the lips or in the mouth
• Sores, welting, or blisters
• Stupor
• Swelling of the face, ankles, hands, feet, or lower legs
• Swollen glands
• Talking or acting with excitement you cannot control
• Temporary blindness
• Trembling or shaking
• Twitching
• Unexplained bleeding or bruising
• Unusual bleeding or bruising
• Unusually warm skin
• Weakness in the arm or leg on one side of the body, sudden and severe
• Weight loss
• Yellowing of the eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• Burning or tingling sensation
• Drowsiness
• Feeling of constant movement of self or surroundings
• Feeling of warmth
• Redness of the face, neck, arms, and occasionally, upper chest
• Relaxed and calm
• Sensation of spinning
• Sleepiness

• Abdominal or stomach discomfort
• Anxiety
• Bad, unusual, or unpleasant (after) taste
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Change in color vision
• Change in taste
• Difficulty seeing at night
• Difficulty with moving
• Discomfort in the jaw, nasal cavity, or throat
• False or unusual sense of well-being
• Feeling strange
• Heartburn
• Increased sensitivity of the eyes to sunlight
• Joint pain, stiffness, or swelling
• Mental confusion
• Muscle aching or cramping
• Neck pain or stiffness
• Red, sore eyes
• Swollen joints
• Tearing of the eyes
• Thirst
• Weakness

• Backache
• Belching
• Bloated or full feeling
• Changes in patterns and rhythms of speech
• Cramps
• Dry heaves
• Excess air or gas in the stomach or intestines
• Extreme thirst
• Heavy bleeding
• Hiccups
• Hunger
• Increased thirst
• Muscle tiredness
• Muscle twitching or jerking
• Pain
• Passing gas
• Reduced appetite
• Rhythmic movement of muscles
• Severe stomach pain with nausea and vomiting
• Tenderness of the skin
• Trouble with speaking

• Deafness
• Panic
• Severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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