In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of fingolimod in the pediatric population. Safety and efficacy have not been established.
Although appropriate studies on the relationship of age to the effects of fingolimod have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution in patients receiving fingolimod.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Adenovirus Vaccine Type 4, Live
- Adenovirus Vaccine Type 7, Live
- Arsenic Trioxide
- Bacillus of Calmette and Guerin Vaccine, Live
- Influenza Virus Vaccine, Live
- Measles Virus Vaccine, Live
- Mumps Virus Vaccine, Live
- Perflutren Lipid Microsphere
- Poliovirus Vaccine, Live
- Rotavirus Vaccine, Live
- Rubella Virus Vaccine, Live
- Smallpox Vaccine
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
- Typhoid Vaccine
- Varicella Virus Vaccine
- Yellow Fever Vaccine
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Angina, unstable (within the past 6 months) or
- Heart attack (within the past 6 months) or
- Heart block (without a pacemaker) or
- Heart failure, decompensated (within the past 6 months) or
- Heart rhythm problem (e.g., QT prolongation) or
- Sick sinus syndrome (without a pacemaker) or
- Stroke (within the past 6 months) or
- Transient ischemic attack (within the past 6 months)—Should not be used in patients with these conditions.
- Bradycardia (slow heartbeat) or
- Breathing problems or
- Hypertension (high blood pressure)—Use with caution. May make these conditions worse.
- Chickenpox (including recent exposure) or
- Infection—There is an increased risk of severe infections affecting other parts of the body.
- Congestive heart failure or
- Heart attack, history of or
- Heart disease (e.g., ischemic cardiac disease) or
- Heart rhythm problems (e.g., arrhythmia) or
- Stroke, history of or
- Syncope (fainting), history of—May increase risk for bradycardia.
- Diabetes or
- Uveitis (inflammation of the eye), history of—Use with caution. May increase risk of having a serious side effect of the eye called macular edema.
- Heart rhythm problem (e.g., congenital long QT syndrome) or
- Hypokalemia (low potassium in the blood) or
- Hypomagnesemia (low magnesium in the blood)—May increase risk for QT prolongation.
- Kidney disease, severe or
- Liver disease, severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.