Drospirenone, Ethinyl Estradiol, and Levomefolate (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Breast pain or tenderness
• Headache, severe and throbbing
• Heavy non-menstrual vaginal bleeding
• Irregular menstrual periods
• Nausea
• Normal menstrual bleeding occurring earlier, possibly lasting longer than expected

• Longer or heavier menstrual periods
• Unusual tiredness or weakness
• Vomiting

• Abdominal or stomach pain
• Chills
• Clay-colored stools
• Dark urine
• Difficulty with breathing
• Dizziness
• Fever
• Headache
• Itching
• Loss of appetite
• Pain in the chest, groin, or legs, especially the calves
• Rash
• Slurred speech
• Sudden loss of coordination
• Sudden, severe weakness or numbness in the arm or leg
• Sudden, unexplained shortness of breath
• Unpleasant breath odor
• Unusual tiredness or weakness
• Vision changes
• Vomiting of blood
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Crying
• Decreased interest in sexual intercourse
• Delusions of persecution, mistrust, suspiciousness, and/or combativeness
• False or unusual sense of well-being
• Inability to have or keep an erection
• Irritability
• Loss in sexual ability, desire, drive, or performance
• Mental depression
• Quick to react or overreact emotionally
• Rapidly changing moods
• Weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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