Aliskiren and Amlodipine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Rapid weight gain
• Tingling of the hands or feet
• Unusual weight gain or loss

• Blurred vision
• Confusion
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Sweating
• Unusual tiredness or weakness

• Abdominal or stomach pain
• Blistering, peeling, or loosening of the skin
• Chills
• Clay-colored stools
• Cough
• Dark urine
• Diarrhea
• Dizziness
• Fever
• Headache
• Itching
• Joint or muscle pain
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Loss of appetite
• Nausea
• Rash
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Seizures
• Sore throat
• Sores, ulcers, or white spots in the mouth or on the lips
• Unpleasant breath odor
• Vomiting of blood
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Acid or sour stomach
• Itching skin
• Lack or loss of strength
• Muscle cramps
• Rash
• Stomach discomfort or upset

• Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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