Acetaminophen (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abnormal breath sounds
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blurred vision
• Confusion
• Convulsions
• Decreased urine
• Difficult or labored breathing
• Difficulty opening the mouth
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Dry mouth
• Headache
• Increased thirst
• Irregular heartbeat
• Lockjaw
• Loss of appetite
• Mood changes
• Muscle pain or cramps
• Muscle spasm, especially of the neck and back
• Nausea or vomiting
• Nervousness
• Numbness or tingling in the hands, feet, or lips
• Pain at the injection site
• Pounding in the ears
• Rapid weight gain
• Shortness of breath
• Slow or fast heartbeat
• Sweating
• Tightness in the chest
• Unusual tiredness or weakness
• Unusual weight gain or loss
• Wheezing

• Blue lips and fingernails
• Bone pain
• Chest pain
• Coughing
• Coughing that sometimes produces a pink frothy sputum
• Difficult, fast, or noisy breathing, sometimes with wheezing
• Drowsiness
• Fast, slow, pounding, or irregular heartbeat or pulse
• Fever
• Increased sweating
• Lower back, side, or stomach pain
• Muscle spasms (tetany) or twitching
• Noisy breathing
• Pain in the arms or legs
• Pale skin
• Rapid breathing
• Rapid heartbeat
• Swelling around the eyes
• Swelling of the feet, ankles, or lower legs
• Trembling
• Trouble breathing
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Weakness
• Weight gain

• Abdominal or stomach pain or tenderness
• Clay colored stools
• Dark urine
• Decreased appetite
• Difficulty with swallowing
• Flu-like symptoms
• Hives
• Itching
• Loss of appetite
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Right upper stomach tenderness
• Skin rash
• Tightness in the chest
• Yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

• Black, tarry stools
• Bleeding gums
• Bloating of the abdomen or stomach
• Blood in the urine or stools
• Chills
• Difficult or painful urination
• General feeling of discomfort or illness
• Light-colored stools
• Pinpoint red spots on the skin
• Sudden decrease in the amount of urine
• Unpleasant breath odor
• Vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Sleeplessness
• Trouble sleeping
• Unable to sleep

• Fear

• Diarrhea
• Difficulty having a bowel movement (stool)
• Dry mouth
• Hyperventilation
• Irritability
• Restlessness
• Shaking

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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