Gadopentetate (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Arm, back, or jaw pain
• Bluish color
• Blurred vision
• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• Changes in skin color
• Chest pain or discomfort
• Chest tightness or heaviness
• Chills
• Confusion
• Cough
• Difficult or labored breathing
• Difficulty with swallowing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fainting
• Fast, pounding, or irregular heartbeat or pulse
• Fever
• Headache
• Headache, severe and throbbing
• Hives
• Irritation of the throat
• Itching
• Loss of bladder control
• Loss of consciousness
• Nausea
• Nervousness
• Noisy breathing
• Pain or swelling of the treated skin
• Paleness of the skin
• Pounding in the ears
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Red or irritated eyes
• Redness, tenderness, itching, burning, or peeling of the skin
• Runny nose
• Seizures
• Shortness of breath
• Skin rash
• Slow or fast heartbeat
• Sneezing
• Sore throat
• Stuffy nose
• Sweating
• Swelling of the foot or leg
• Swelling or puffiness of the face
• Tenderness
• Total body jerking
• Unusual tiredness or weakness
• Wheezing

• Agitation
• Blistering, peeling, or loosening of the skin
• Bluish color of the fingernails, lips, skin, palms, or nail beds
• Burning or itching of the skin
• Change in consciousness
• Coma
• Coughing that sometimes produces a pink frothy sputum
• Decreased urine output
• Depression
• Diarrhea
• Difficult, fast, or noisy breathing, sometimes with wheezing
• Difficulty with speaking
• Frequent strong or increased urge to urinate
• Hoarseness
• Hostility
• Increased sweating
• Irritability
• Joint or muscle pain
• Joint stiffness
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Lethargy
• Limited range of motion in the arms and legs
• Muscle twitching or weakness
• No blood pressure or pulse
• No breathing
• Pain that is deep in the hip bone or ribs
• Pain, redness, or swelling in the arm or leg
• Rapid weight gain
• Red or dark patches on the skin
• Shakiness in the legs, arms, hands, or feet
• Skin swelling, hardening, or tightening
• Slow or irregular breathing
• Sores, ulcers, or white spots in the mouth or on the lips
• Spots on your skin resembling a blister or pimple
• Stopping of heart
• Stupor
• Swelling of the face, ankles, or hands
• Tenderness
• Tightness in the chest
• Trembling or shaking of the hands or feet
• Troubled breathing
• Unconsciousness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

• Abdominal or stomach discomfort or pain
• Back pain
• Bad, unusual, or unpleasant (after) taste
• Burning, dry, or itching eyes
• Change in taste
• Continuing ringing or buzzing or other unexplained noise in the ears
• Decrease or change in vision
• Difficulty having a bowel movement (stool)
• Discharge or excessive tearing
• Double vision
• Dry mouth
• Ear pain
• Eye pain
• Feeling cold or warm
• Hearing loss
• Hives or welts
• Hyperventilation
• Increased salivation
• Lack or loss of strength
• Loss of appetite
• Nervousness
• Pain in the tooth
• Redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
• Restlessness
• Seeing double
• Skin rash
• Sleepiness or unusual drowsiness
• Tearing of the eyes
• Thirst
• Trouble sleeping
• Uncontrolled eye movements
• Vomiting
• Weight loss

• Blurred or loss of vision
• Change in sense of smell
• Difficulty with moving
• Disturbed color perception
• Double vision
• Halos around lights
• Muscle pain or stiffness
• Night blindness
• Overbright appearance of lights
• Poor hearing
• Tunnel vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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