Factor Xiii Human (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Bloody nose
• Bruise
• Collection of blood under the skin
• Deep, dark purple bruise
• Fever
• Itching, pain, redness, or swelling

• Blurred vision
• Chills
• Confusion
• Cough
• Difficult or labored breathing
• Difficulty swallowing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fast heartbeat
• Hives
• Nausea
• Pain in the chest, groin, or legs, especially the calves
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Red, scaly, swollen, or peeling areas of the skin
• Severe, sudden headache
• Shortness of breath
• Skin rash
• Slurred speech
• Sudden loss of coordination
• Sudden, severe weakness or numbness in the arm or leg
• Sudden, unexplained shortness of breath
• Sweating
• Tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
• Tightness in the chest
• Unusual tiredness or weakness
• Vision changes
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach pain
• Diarrhea
• Difficulty with moving
• General feeling of discomfort or illness
• Headache
• Joint pain
• Loss of appetite
• Muscle aches and pains
• Muscle stiffness
• Runny nose
• Shivering
• Sore throat
• Sweating
• Trouble sleeping
• Vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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