Rilpivirine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Abdominal or stomach fullness
• Changes in behavior
• Cloudy or bloody urine
• Discouragement
• Feeling sad or empty
• Gaseous abdominal or stomach pain
• High blood pressure
• Indigestion
• Irritability
• Lack of appetite
• Loss of interest or pleasure
• Recurrent fever
• Severe nausea or vomiting
• Sleeplessness
• Swelling of the face, feet, or lower legs
• Thoughts of killing oneself
• Tiredness
• Trouble concentrating
• Trouble sleeping
• Unable to sleep
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach discomfort
• Abnormal dreams
• Decreased appetite
• Diarrhea
• Dizziness
• Fear or nervousness
• Headache
• Nausea
• Rash
• Sleepiness or unusual drowsiness
• Unusual tiredness or weakness
• Vomiting

• Decreased amount of fat from your legs, arms, or face
• Increased amount of fat in the upper back and neck, or around the chest and stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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