Hydrocodone, Chlorpheniramine, and Pseudoephedrine (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Fainting
• Lightheadedness
• Shakiness in the legs, arms, hands, or feet
• Trembling or shaking of the hands or feet

• Abdominal or stomach cramps or pain
• Bloating
• Blurred vision
• Bulging soft spot on the head of an infant
• Change in the ability to see colors, especially blue or yellow
• Confusion
• Constipation
• Convulsions
• Decrease in the frequency of urination
• Decrease in the urine volume
• Diarrhea
• Difficult or troubled breathing
• Difficulty in passing urine (dribbling)
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Drowsiness
• Fainting
• Fast, slow, or irregular heartbeat
• Headache
• Irregular, fast or slow, or shallow breathing
• Loss of appetite
• Nervousness
• Painful urination
• Pale or blue lips, fingernails, or skin
• Pounding in the ears
• Shortness of breath
• Sore throat
• Spasm of the throat
• Sweating
• Tightness of the chest
• Unusual tiredness or weakness
• Vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Disturbed color perception
• Double vision
• Dry mouth
• False or unusual sense of well-being
• Fear or nervousness
• Halos around lights
• Hyperventilation
• Nausea
• Night blindness
• Overbright appearance of lights
• Relaxed and calm
• Restlessness
• Sleepiness or unusual drowsiness
• Sleeplessness
• Trouble sleeping
• Tunnel vision
• Unable to sleep
• Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

• Acid or sour stomach
• Belching
• Bigger, dilated, or enlarged pupils (black part of the eye)
• Bloating
• Change in color vision
• Chills
• Cold sweats
• Coma
• Continuing ringing or buzzing or other unexplained noise in the ears
• Cool, pale skin
• Darkened urine
• Depression
• Difficulty seeing at night
• Feeling of constant movement of self or surroundings
• Fever
• Flushing or redness of the skin
• Full feeling
• Hearing loss
• Heartburn
• Hives or welts
• Increased appetite
• Increased hunger
• Increased in sexual ability, desire, drive, or performance
• Increased interest in sexual intercourse
• Increased sensitivity of the eyes to sunlight
• Increased sweating
• Indigestion
• Itching skin
• Loss of appetite
• Nightmares
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Pressure in the stomach
• Seizures
• Sensation of spinning
• Skin rash
• Slurred speech
• Stomach discomfort or upset
• Sugar in the urine
• Swelling of the abdominal or stomach area
• Swelling of the breasts or breast soreness in both females and males
• Unusually warm skin
• Watering of the eyes
• Yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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