Rivaroxaban (Oral Route)

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Proper Use

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

The 10-mg tablets can be taken with or without food. The 15 and 20 mg tablets should be taken with food .

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  • For prevention of deep venous thrombosis (hip replacement surgery):
    • Adults—10 milligrams (mg) once a day for 35 days. The starting dose should be taken at least 6 to 10 hours after surgery.
    • Children—Use and dose must be determined by your doctor.
  • For prevention of deep venous thrombosis (knee replacement surgery):
    • Adults—10 milligrams (mg) once a day for 12 days. The starting dose should be taken at least 6 to 10 hours after surgery.
    • Children—Use and dose must be determined by your doctor.
  • For prevention of reoccurring deep venous thrombosis and pulmonary embolism:
    • Adults—20 milligrams (mg) once a day with food.
    • Children—Use and dose must be determined by your doctor.
  • For prevention of stroke and blood clots in patients with nonvalvular atrial fibrillation:
    • Adults—15 or 20 milligrams (mg) once a day, taken with the evening meal.
    • Children—Use and dose must be determined by your doctor.
  • For treatment of deep venous thrombosis and pulmonary embolism:
    • Adults—At first, 15 milligrams (mg) two times a day, taken with food for the first 21 days. Then, your doctor may give you 20 mg once a day, taken at the same time each day with food.
    • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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