Brentuximab (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Black, tarry stools
• Bleeding gums
• Blood in the urine or stools
• Body aches or pain
• Burning, numbness, tingling, or painful sensations
• Chills
• Cough
• Difficult or labored breathing
• Difficulty with breathing
• Ear congestion
• Fever
• Headache
• Loss of voice
• Lower back or side pain
• Pain
• Painful or difficult urination
• Pale skin
• Pinpoint red spots on the skin
• Shortness of breath
• Sneezing
• Sore throat
• Stuffy or runny nose
• Swollen, painful, or tender lymph glands in the neck, armpit, or groin
• Tightness in the chest
• Troubled breathing with exertion
• Ulcers, sores, or white spots in the mouth
• Unsteadiness or awkwardness
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Weakness in the arms, hands, legs, or feet
• Wheezing

• Anxiety
• Back pain
• Bladder pain
• Blistering, peeling, or loosening of the skin
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blurred vision
• Chest pain
• Cloudy urine
• Confusion
• Convulsions
• Diarrhea
• Dizziness or lightheadedness
• Drowsiness
• Fainting
• Fast heartbeat
• Frequent urge to urinate
• General feeling of discomfort or illness
• Irregular heartbeat
• Itching
• Joint pain, stiffness, or swelling
• Muscle pain
• Rapid weight gain
• Red skin lesions, often with a purple center
• Red, irritated eyes
• Severe pain in the chest
• Stomach pain
• Sudden onset of severe breathing difficulty
• Sudden shortness of breath or troubled breathing
• Thickening of bronchial secretions
• Troubled breathing
• Unusual weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Decreased appetite or weight
• Difficulty having a bowel movement (stool)
• Difficulty with moving
• Hair loss or thinning of the hair
• Muscle spasms
• Muscle stiffness
• Nausea
• Night sweats
• Pain in the arms or legs
• Rash
• Sleeplessness
• Trouble with sleeping
• Unable to sleep
• Vomiting

• Dry skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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