Dolasetron (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Chest pain or discomfort
• Lightheadedness, dizziness, or fainting
• Shortness of breath
• Slow or irregular heartbeat
• Unusual tiredness or weakness

• Chills
• Decrease in the amount of urine
• Fast, pounding, or irregular heartbeat or pulse
• Fever

• Agitation
• Black, tarry stools
• Bleeding gums
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blood in the urine or stools
• Blurred vision
• Burning while urinating
• Changes in skin color
• Coma
• Confusion
• Cough
• Depression
• Difficult or labored breathing
• Difficult or painful urination
• Difficulty with swallowing
• Dizziness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Frequent urination
• Headache
• Hives or welts
• Hostility
• Increased volume of pale, dilute urine
• Irritability
• Itching of the skin
• Lethargy
• Muscle twitching
• Nausea
• Noisy breathing
• Numbness and tingling of the face, fingers, or toes
• Pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
• Pain, tenderness, or swelling of the foot or leg
• Pale skin
• Pale, bluish-colored, or cold hands or feet
• Pinpoint red or purple spots on the skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Rapid weight gain
• Redness of the skin
• Seizures
• Skin rash
• Stupor
• Sweating
• Swelling of the face, ankles, or hands
• Tightness in the chest
• Tingling of the hands or feet
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual weight gain or loss
• Weak or absent pulses in the legs
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Diarrhea

• Acid or sour stomach
• Belching
• Heartburn
• Indigestion
• Pain
• Stomach discomfort, upset, or pain

• Abnormal dreams
• Agitation
• Bad, unusual, or unpleasant (after) taste
• Bloating
• Bloody nose
• Change in color vision
• Change in taste
• Changes in vision
• Continuing ringing or buzzing or other unexplained noise in the ears
• Darkened urine
• Difficulty having a bowel movement (stool)
• Difficulty seeing at night
• Difficulty with moving
• Feeling of constant movement of self or surroundings
• Feeling of unreality
• Feeling of warmth
• Hearing loss
• Increased sensitivity of the eyes to sunlight
• Increased sweating
• Joint pain
• Loss of appetite
• Muscle aching or cramping
• Muscle pain or stiffness
• Pain or burning sensation at the injection site
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Redness of the face, neck, arms, and occasionally, upper chest
• Sensation of spinning
• Sense of detachment from self or body
• Shakiness and unsteady walk
• Shakiness in the legs, arms, hands, or feet
• Swollen joints
• Trembling or shaking of the hands or feet
• Unsteadiness, trembling, or other problems with muscle control or coordination
• Vomiting
• Weight loss
• Yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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