Deferiprone (Oral Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

• Black, tarry stools
• Chills
• Cough
• Fever
• Lower back or side pain
• Painful or difficult urination
• Pale skin
• Shortness of breath
• Sore throat
• Ulcers, sores, or white spots in the mouth
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Fever with or without chills
• General feeling of tiredness or weakness
• Hoarseness

• Abdominal or stomach pain
• Anxiety
• Bleeding gums
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Blood in the urine or stools
• Blurred vision
• Chest pain or discomfort
• Clay-colored stools
• Confusion
• Convulsions
• Dark urine
• Decreased urination
• Dilated neck veins
• Dizziness or lightheadedness
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Drowsiness
• Dry mouth
• Extreme fatigue
• Fainting
• Fast or irregular heartbeat
• Headache
• Hives
• Increase in heart rate
• Increased sweating
• Irregular breathing
• Irritation
• Itching
• Joint pain, stiffness, or swelling
• Large, flat, blue or purplish patches in the skin
• Loss of appetite
• Muscle tremors
• Nausea
• Nervousness
• Painful knees and ankles
• Pinpoint red spots on the skin
• Pounding in the ears
• Raised red swellings on the skin, the buttocks, legs, or ankles
• Rapid weight gain
• Rapid, deep breathing
• Rapid, shallow breathing
• Rash
• Redness of the skin
• Restlessness
• Severe nausea or vomiting
• Slow heartbeat
• Sneezing
• Spots on your skin resembling a blister or pimple
• Stomach cramps
• Sudden shortness of breath or troubled breathing
• Sugar in the urine
• Sunken eyes
• Sweating
• Swelling around the eyes
• Swelling of the eyelids, face, lips, hands, or feet
• Thirst
• Tightness in the chest
• Tingling of the hands or feet
• Trouble with balance
• Troubled breathing or swallowing
• Unpleasant breath odor
• Unusual weight gain or loss
• Vision changes
• Vomiting of blood
• Weight gain
• Wheezing
• Wrinkled skin
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Abdominal or stomach discomfort
• Difficulty with moving
• Muscle pain or stiffness
• Reddish or brow discoloration of the urine

• Acid or sour stomach
• Back pain
• Belching
• Diarrhea
• Heartburn
• Increased or decreased appetite
• Indigestion
• Pain in the arms or legs
• Stomach upset

• Bloody nose
• Clenching, gnashing, or grinding teeth
• Constipation
• Coughing or spitting up blood
• Depression
• Difficulty opening the mouth
• Difficulty with speaking
• Drooling
• Hives or welts
• Impaired psychomotor skills
• Increased sensitivity of the skin to sunlight
• Lockjaw
• Loss of appetite
• Loss of balance control
• Muscle spasm, especially of the neck and back
• Muscle trembling, jerking, or stiffness
• Pains in the stomach, side, or abdomen, possibly radiating to the back
• Redness or other discoloration of the skin
• Restlessness
• Severe sunburn
• Shuffling walk
• Sleepiness or unusual drowsiness
• Stiffness of the limbs
• Stomach bloating, burning, cramping, or pain
• Twisting movements of the body
• Uncontrolled movements, especially of the face, neck, and back

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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