Taliglucerase Alfa (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Chest pain or discomfort
• Dizziness
• Facial swelling
• Fever or chills
• Headache
• Hives or welts
• Itching
• Nausea or vomiting
• Redness of the skin
• Shortness of breath
• Skin rash
• Weakness

• Difficult or labored breathing
• Difficulty with swallowing
• Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Tightness in the chest
• Unusual tiredness or weakness
• Wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Back pain
• Bladder pain
• Bloody or cloudy urine
• Body aches or pain
• Congestion
• Difficult, burning, or painful urination
• Dryness or soreness of the throat
• Frequent urge to urinate
• Lack or loss of strength
• Runny nose
• Sneezing
• Voice changes

• Abdominal or stomach pain
• Bloating or swelling of the face, arms, hands, lower legs, or feet
• Bone pain
• Diarrhea
• Muscle spasms
• Tingling of the hands or feet
• Trouble with sleeping
• Unusual weight gain or loss

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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