Fentanyl (Injection Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Chest pain or discomfort
• Difficult or troubled breathing
• Irregular, fast or slow, or shallow breathing
• Lightheadedness, dizziness, or fainting
• Pale or blue lips, fingernails, or skin
• Severe muscle stiffness
• Shortness of breath
• Slow or irregular heartbeat
• Unusual tiredness

• Blurred vision
• Change in consciousness
• Chills
• Confusion
• Cough
• Difficulty with swallowing
• Fast heartbeat
• Feeling cold
• Headache
• Hives
• Inability to move the eyes
• Inability to sit still
• Increased blinking or spasms of the eyelid
• Itching
• Low blood pressure or pulse
• Nervousness
• Pounding in the ears
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Restlessness
• Seeing, hearing, or feeling things that are not there
• Skin rash
• Sticking out the tongue when not meaning to
• Sweating
• Tightness in the chest
• Uncontrolled twisting movements of the neck, trunk, arms, or legs
• Unusual facial expressions

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Increased sweating
• Redness of the skin
• Vomiting
• Welts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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