Vincristine Liposome (Intravenous Route)

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Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

• Abdominal or stomach pain
• Black, tarry stools
• Bleeding gums
• Blood in the urine or stools
• Blurred vision
• Burning, tingling, numbness or pain in the hands, arms, feet, or legs
• Change in consciousness
• Change in muscle reflexes
• Chest pain
• Chills
• Confusion
• Cough
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fever
• Increased sensitivity to pain or touch
• Low blood pressure or pulse
• Lower back or side pain
• Nerve pain
• Painful or difficult urination
• Pale skin
• Pinpoint red spots on the skin
• Sensation of pins and needles
• Severe constipation
• Severe vomiting
• Shortness of breath
• Sneezing
• Sore throat
• Stabbing pain
• Sweating
• Tightness in the chest
• Troubled breathing
• Ulcers, sores, or white spots in the mouth
• Unsteadiness or awkwardness
• Unusual bleeding or bruising
• Unusual tiredness or weakness

• Blue lips, fingernails, or skin
• Irregular, fast or slow, or shallow breathing

• Abdominal or stomach tenderness
• Clay colored stools
• Dark urine
• Decreased appetite
• Headache
• Itching
• Joint pain, stiffness, or swelling
• Loss of appetite
• Nausea and vomiting
• Skin rash
• Swelling of the feet or lower legs
• Yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Lack or loss of strength
• Mental depression or anxiety
• Muscle weakness
• Nightmares or unusually vivid dreams

• Redness, pain, or swelling at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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