Dumping syndrome

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Causes

By Mayo Clinic staff

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Illustration of pyloric valve, stomach and upper part of small intestine (duodenum)
Stomach and pyloric valve

In dumping syndrome, food and gastric juices from your stomach move to your small intestine in an unregulated, abnormally fast manner. This accelerated process is most often related to changes in your stomach associated with surgery. For example, when the opening (pylorus) between your stomach and the first portion of the small intestine (duodenum) has been damaged or removed during an operation, dumping syndrome may develop.

Dumping syndrome may occur at least mildly in one-quarter to one-half of people who have had gastric bypass surgery. It develops most commonly within weeks after surgery, or as soon as you return to your normal diet. The more stomach removed or bypassed, the more likely that the condition will be severe. It sometimes becomes a chronic disorder.

Gastrointestinal hormones also are believed to play a role in this rapid dumping process.

References
  1. Rapid gastric emptying. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/rapidgastricemptying/. Accessed Feb. 18, 2010.
  2. Tack J, et al. Pathophysiology, diagnosis and management of postoperative dumping syndrome. Nature Reviews Gastroenterology and Hepatology. 2009;6:583.
  3. Mun EC, et al. Complications of bariatric surgery. http://www.uptodate.com/home/index.html. Accessed Feb. 22, 2010.
  4. Mun EC, et al. Medical management of patients after bariatric surgery. http://www.uptodate.com/home/index.html. Accessed Feb. 22, 2010.
  5. Deitel, M. The change in the dumping syndrome concept. Obesity Surgery. 2008;18:1622.
  6. Hejazi RA, et al. Dumping syndrome: Establishing criteria for diagnosis and identifying new etiologies. Digestive Diseases and Sciences. 2010;55:117.
  7. Dumping syndrome. University of Wisconsin School of Medicine and Public Health. http://www.uwhealth.org/healthfacts/B_EXTRANET_HEALTH_INFORMATION-FlexMember-Show_Public_HFFY_1104449365863.html. Accessed Feb. 27, 2010.
  8. Pectin. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Feb. 27, 2010.
  9. Guar gum. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Feb. 27, 2010.
  10. Black psyllium. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Feb. 27, 2010.
  11. Blond psyllium. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Feb. 27, 2010.
DS00715 April 3, 2010

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