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Complications
By Mayo Clinic staffDupuytren's contracture can make it difficult to perform certain functions using your hand. Since the thumb and index finger aren't usually affected, many people don't experience much inconvenience or disability with fine activities such as writing. But as Dupuytren's contracture progresses, it can limit your ability to fully open your hand and make it difficult to grasp large objects or to get your hand into narrow places.
- Calandruccio JH. Dupuytren contracture. In: Canale ST, et al. Campbell's Operative Orthopaedics. 11th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/185412162-4/958195331/1584/560.html#4-u1.0-B978-0-323-03329-9..50075-1_3999. Accessed Feb. 24, 2010.
- Sheon RP, et al. Dupuytren's contracture. http://www.uptodate.com/home/index.html. Accessed Feb. 24, 2010.
- Stretanski MF. Dupuytren contracture. In: Frontera WR, et al. Essentials of Physical Medicine and Rehabilitation. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/185680318-3/958880137/1678/28.html#4-u1.0-B978-1-4160-4007-1..50027-4_405. Accessed Feb. 25, 2010.
- Dupuytren's contracture. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00008. Accessed Feb. 24, 2010.
- Rayan GM. Nonoperative treatment of Dupuytren's disease. Journal of Hand Surgery. 2008;33A:1208.
- Amadio PC (expert opinion). Mayo Clinic, Rochester, Minn. March 8, 2010.
- Hurst LC, et al. Injectable collagenase clostridium histolyticum for Dupuytren's contracture. New England Journal of Medicine. 2009;361:968.
- Xiaflex (prescribing information). Malvern, Pa.: Auxilium Pharmaceuticals, Inc.; 2010. http://www.xiaflex.com/XIAFLEX_prescribing_info.jsp. Accessed March 15, 2010.
- Mercier LR. Dupuytren's contracture. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/186345095-3/960507000/2088/198.html#4-u1.0-B978-0-323-05609-0..00013-7--sc0110_4003. Accessed Feb. 25, 2010.
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